§ 69403.14. Ototoxicity.

Latest version.

(a) The ototoxicity hazard trait is defined as the occurrence of adverse effects on the structure or function of the inner ear or the vestibulo-cochlear nerve, or auditory portions of the central nervous system, which could result in temporary or permanent disturbances of hearing, balance, or both following exposure to a chemical substance.
(b) Toxicological endpoints for ototoxicity include, but are not limited to those indicating: hearing impairment; abnormal balance; changes to cellular components of the inner ear; change in auditory response or electrical activity in the vestibulo-cochlear nerve or auditory areas of the brain.
(c) Other relevant ototoxicity data include but are not limited to: in vitro indications of ototoxicity; structural or mechanistic similarity to other chemical substances that are ototoxic.

HISTORY

1. New section filed 12-20-2011; operative 1-29-2012 (Register 2011, No. 51).

Note

Note: Authority cited: Sections 25256.1 and 59012, Health and Safety Code. Reference: Sections 25256.1 and 59012, Health and Safety Code.

                    
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