§ 69403.10. Nephrotoxicity and Other Toxicity to the Urinary System.  


Latest version.
  • (a) The nephrotoxicity hazard trait is defined as the occurrence of adverse effects on the structure or function of the kidney and other components of the urinary system following exposure to a chemical substance.
    (b) Toxicological endpoints for nephrotoxicity and other urinary system toxicity include, but are not limited to those indicating: abnormal urine volume or chemistry; abnormal blood chemistry; alterations in glomerular filtration rate or tubular re-absorptive capacity; pathological changes to the kidney; formation of calculi in the ureter or bladder; muscular or epithelial damage in the urinary bladder.
    (c) Other relevant data include, but are not limited to: in vitroindicators of nephrotoxicity; structural or mechanistic similarity to other chemical substances that are nephrotoxic.
HISTORY
1. New section filed 12-20-2011; operative 1-29-2012 (Register 2011, No. 51).

Note

Note: Authority cited: Sections 25256.1 and 59012, Health and Safety Code. Reference: Sections 25256.1 and 59012, Health and Safety Code.