§ 69403.6. Hematotoxicity.

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(a) The hematotoxicity hazard trait is defined as the occurrence of adverse effects on blood or blood-forming tissues following exposure to a chemical substance.
(b) Toxicological endpoints for hematotoxicity include, but are not limited to those indicating: alterations in the number, types or lifetime of circulating blood cells, or in the ratio of cell types; decrease in the oxygen transporting capacity of hemoglobin or red blood cells; increase or decrease in blood clotting activity resulting from interference in platelet response or function or other causes; bone marrow toxicity; aplastic, hemolytic or myelodysplastic anemia.
(c) Other relevant data include but are not limited to: in vitromeasures of toxicity in isolated blood cells or blood-forming tissues; structural or mechanistic similarity to other chemical substances that are hematotoxic.

HISTORY

1. New section filed 12-20-2011; operative 1-29-2012 (Register 2011, No. 51).

Note

Note: Authority cited: Sections 25256.1 and 59012, Health and Safety Code. Reference: Sections 25256.1 and 59012, Health and Safety Code.

                    
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